Transcriptome analysis of cattle PBMCs induced with E. coli antigen causing mastitis

نویسندگان

چکیده

Endotoxin lipopolysaccharide (LPS) is the most powerful and effective immunostimulant key virulence factor produced by Escherichia coli (E. coli) accountable for many of inflammatory changes observed during bovine mastitis. In this study, whole-transcriptomic gene in peripheral blood mononuclear cells (PBMCs) stimulated with LPS were compared to control group analyzed RNA sequencing. A total 358 differentially expressed genes (DEGs) identified LPS-induced as upregulated against group, an adjusted Padj

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ژورنال

عنوان ژورنال: Pharma innovation

سال: 2023

ISSN: ['2277-7695', '2349-8242']

DOI: https://doi.org/10.22271/tpi.2023.v12.i2e.18437